CDK2AP1 — Cyclin dependent kinase 2 associated protein 1
CDK2AP1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CDK2AP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Polycomb Transcriptional Control DNA/chromatin regulation | AMFR, ATMIN, BRD7, CBX4, CCNY, CD81, CSNK1E, CSNK1G2 +17 more | |
| Monocytes | Monocyte Identity Innate immunity | C1orf162, CD68, CMTM7, DBNDD2, EIF4EBP3, MIF, NME2, TBXAS1 | View in SCUBA |
About the gene
| Synonyms | doc-1, DOC1, DORC1, p12DOC-1, ST19 |
|---|---|
| Chromosome | 12: 123250112-123272334 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Cell cycle, Transcription, Transcription regulation |
Function
Inhibitor of cyclin-dependent kinase CDK2 (By similarity). Also acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.