CHAMP1 — Chromosome alignment maintaining phosphoprotein 1
CHAMP1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CHAMP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | mRNA Decay Trafficking RNA processing & translation | CEP290, DCP2, GTF2I, HPS3, IRAK4, IWS1, LIN52, MYO9A +4 more |
About the gene
| Synonyms | C13orf8, CAMP, CHAMP, ZNF828 |
|---|---|
| Chromosome | 13: 114314482-114337626 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Human disease related genes, Predicted intracellular proteins |
Function
Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.