HPS3 — HPS3 biogenesis of lysosomal organelles complex 2 subunit 1
HPS3 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
HPS3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | mRNA Decay Trafficking RNA processing & translation | CEP290, CHAMP1, DCP2, GTF2I, IRAK4, IWS1, LIN52, MYO9A +4 more | |
| Innate lymphoid cells | JAK-STAT Cytokine Signaling Inflammation | AASDHPPT, ARHGAP9, CHURC1, CIDEB, CSK, DCAF7, DENND2D, EDEM2 +23 more | View in SCUBA |
| Macrophages | ER-Golgi Trafficking Vesicular traficking | B4GALT5, CDC27, CLCN3, CUL1, GFPT1, KCTD20, PPTC7, PTPN9 +5 more | View in SCUBA |
| Mucosal-associated invariant T cell | Integrin Actin Adhesion migration & adhesion | ACTR2, ANKRD10, ATP2B1, DDX46, HP1BP3, JAK1, LINS1, LRIF1 +11 more |
About the gene
| Synonyms | BLOC2S1, SUTAL |
|---|---|
| Chromosome | 3: 149129638-149173732 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins |
Function
Involved in early stages of melanosome biogenesis and maturation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.