MYO9A — Myosin IXA
MYO9A belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MYO9A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | mRNA Decay Trafficking RNA processing & translation | CEP290, CHAMP1, DCP2, GTF2I, HPS3, IRAK4, IWS1, LIN52 +4 more | |
| Lymphatic endothelial | Polarized Vesicle Trafficking migration & adhesion | ELMO1, EXOC4, EXOC6B, IMMP2L, L3MBTL4, LRBA, LRMDA, PARD3B +5 more | View in SCUBA |
| Macrophages | Rho GTPase Signaling Cytoskeletal | ABHD18, AFF1, ARHGEF7, DIP2B, DNAAF9, DOCK11, EVI5, GNAQ +24 more | View in SCUBA |
About the gene
| Synonyms | FLJ11061, FLJ13244, MGC71859 |
|---|---|
| Chromosome | 15: 71822291-72118577 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Actin-binding, GTPase activation, Motor protein, Myosin |
Function
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating it's GTPase activity in neurons. Required for the regulation of neurite branching and motor neuron axon guidance (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.