CIPC — CLOCK interacting pacemaker
CIPC belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CIPC's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | PPARG Lipid Metabolism Nutrient processing | ABHD5, AXDND1, CDK2AP2, FAM107B, GCLM, MIER1, NAA60, NOL4L +4 more | View in SCUBA |
About the gene
| Synonyms | KIAA1737 |
|---|---|
| Chromosome | 14: 77098126-77117287 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Repressor |
| Biological process | Biological rhythms, Transcription, Transcription regulation |
Function
Transcriptional repressor which may act as a negative- feedback regulator of CLOCK-BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate BMAL1-dependent phosphorylation of CLOCK. However, the physiological relevance of these observations is unsure, since experiments in an animal model showed that CIPC is not critially required for basic circadian clock
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.