CNOT10 — CCR4-NOT transcription complex subunit 10
CNOT10 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CNOT10's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Chromatin Repression DNA/chromatin regulation | CAPN12, CFAP210, EPS8L2, FKBP5, H1-10, HAGHL, IL6ST, METTL24 +8 more |
About the gene
| Synonyms | FLJ12890, FLJ13165 |
|---|---|
| Chromosome | 3: 32685145-32773875 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation |
Function
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.