EPS8L2 — EPS8 like 2
EPS8L2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EPS8L2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Mature enterocyte differentiation Absorption | ABCC2, ACSF2, AOC1, CDC14A, CEP350, EEPD1, GRAMD1C, MXI1 +5 more | View in SCUBA |
| Gamma-delta T cells | Chromatin Repression DNA/chromatin regulation | CAPN12, CFAP210, CNOT10, FKBP5, H1-10, HAGHL, IL6ST, METTL24 +8 more |
About the gene
| Synonyms | FLJ21935, FLJ22171, MGC3088 |
|---|---|
| Chromosome | 11: 694438-727727 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
Function
Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.