CAPN12 — Calpain 12
CAPN12 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CAPN12's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Chromatin Repression DNA/chromatin regulation | CFAP210, CNOT10, EPS8L2, FKBP5, H1-10, HAGHL, IL6ST, METTL24 +8 more | |
| Innate lymphoid cells | NK Cytotoxic Regulation Cytotoxicity | ARHGAP30, BIN2, CHD9, CLK1, CTSC, CYB5B, DDX27, DNMT1 +29 more | View in SCUBA |
| Natural Killer cells | NK Homeostatic Survival Immune regulation | ACAP1, ARHGAP30, FYB1, GIMAP6, GPR174, IRF2, SLFN5, STOM +1 more | View in SCUBA |
About the gene
| Chromosome | 19: 38730187-38769904 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins |
| Molecular function | Hydrolase, Protease, Thiol protease |
Function
Calcium-regulated non-lysosomal thiol-protease
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.