CSF2RA — Colony stimulating factor 2 receptor subunit alpha
CSF2RA belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CSF2RA's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Integrated Stress Response Stress | AKAP17A, ANKHD1, APBB3, C15orf39, DDIT3, DDX39B, EMD, GPS2 +17 more | View in SCUBA |
| Monocytes | Complement Receptor Activation Lysosomal & pahgocytosis | AVPI1, C5AR1, C5AR2, CLEC7A, MAT2A, METRNL, PTPRE, RAB20 +1 more | View in SCUBA |
About the gene
| Synonyms | alphaGMR, CD116, CSF2R |
|---|---|
| Chromosome | X: 1268800-1310381 |
| Predicted location | Membrane, Secreted |
| Essential gene | No |
| Protein class | Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins |
| Molecular function | Receptor |
Function
Low affinity receptor for granulocyte-macrophage colony- stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.