AKAP17A — A-kinase anchoring protein 17A
AKAP17A belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AKAP17A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | gd T Cell Identity T cell maturation | CNNM3, GALNT11, KCNA3, MECP2, PIEZO1, PLXNC1, RASGEF1A, RERE +6 more | |
| Macrophages | Integrated Stress Response Stress | ANKHD1, APBB3, C15orf39, CSF2RA, DDIT3, DDX39B, EMD, GPS2 +17 more | View in SCUBA |
| Mucosal-associated invariant T cell | Transcription Factor Activity DNA/chromatin regulation | BTAF1, HNRNPH1, HSPA9, IKZF5, LCOR, NDEL1, POLR2M, SDE2 +3 more |
About the gene
| Synonyms | 721P, CCDC133, CXYorf3, DXYS155E, MGC39904, SFRS17A, XE7, XE7Y |
|---|---|
| Chromosome | X: 1591604-1602520 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | RNA-binding |
| Biological process | mRNA processing, mRNA splicing |
Function
Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.