CTBS — Chitobiase
CTBS belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CTBS's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Membrane Trafficking Protein processing & ER | B4GALT1, BTF3L4, CELF1, CLTC, CSNK1G3, DERL2, DYNC1LI2, EMC9 +23 more | View in SCUBA |
| Macrophages | Macrophage Endocytic Signaling Lysosomal & pahgocytosis | APLP2, ARHGAP30, ARHGEF2, ATF6B, BAG6, CLSTN1, CMTR2, DSE +20 more | View in SCUBA |
About the gene
| Synonyms | CTB |
|---|---|
| Chromosome | 1: 84549611-84574480 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | Glycosidase, Hydrolase |
Function
Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N- acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.