ARHGAP30 — Rho GTPase activating protein 30
ARHGAP30 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARHGAP30's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | B-cell activation B cell maturation | ADAM19, CD164, CD19, CD47, CLN8, CPEB4, ELK3, FNIP1 +15 more | View in SCUBA |
| CD4⁺ T cells | JAK-STAT Signaling Immune regulation | CELF2, DDX17, DNAJC1, GSDMD, HCLS1, JAK3, MBNL1, N4BP2L2 +7 more | View in SCUBA |
| Gamma-delta T cells | Butyrophilin gd Activation TCR Signaling | ABI1, ADD3, ANXA6, ARHGAP1, ARHGAP25, ARHGEF2, BTN3A1, BTN3A3 +16 more | |
| Innate lymphoid cells | NK Cytotoxic Regulation Cytotoxicity | BIN2, CAPN12, CHD9, CLK1, CTSC, CYB5B, DDX27, DNMT1 +29 more | View in SCUBA |
| Macrophages | Macrophage Endocytic Signaling Lysosomal & pahgocytosis | APLP2, ARHGEF2, ATF6B, BAG6, CLSTN1, CMTR2, CTBS, DSE +20 more | View in SCUBA |
| Mucosal-associated invariant T cell | Chromatin Remodeling DNA/chromatin regulation | ANP32E, CANX, DCTN1, EPRS1, FLII, HK1, JAK3, LASP1 +9 more | |
| Natural Killer cells | NK Homeostatic Survival Immune regulation | ACAP1, CAPN12, FYB1, GIMAP6, GPR174, IRF2, SLFN5, STOM +1 more | View in SCUBA |
About the gene
| Synonyms | FLJ00267 |
|---|---|
| Chromosome | 1: 161046946-161069970 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | GTPase activation |
Function
GTPase-activating protein (GAP) for RAC1 and RHOA, but not for CDC42
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.