DENND1C — DENN domain containing 1C
DENND1C belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DENND1C's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Mitochondrial RNA Processing Mitochondrial & OxPhos | ABR, DARS1, GTDC1, MRPS30, PDCD4, PMPCB, POLG, PRKD2 +11 more |
About the gene
| Synonyms | FAM31C, FLJ22757 |
|---|---|
| Chromosome | 19: 6467207-6482557 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Guanine-nucleotide releasing factor |
Function
Guanine nucleotide exchange factor (GEF) which may activate RAB8A, RAB13 and RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.