DSN1 — DSN1 component of MIS12 kinetochore complex
DSN1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DSN1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | Replication Licensing Cell cycle | ACYP1, DDB2, GMNN, HIRIP3, ITGB3BP, LSM3, MAGOHB, NUDT1 +8 more | View in SCUBA |
About the gene
| Synonyms | C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13 |
|---|---|
| Chromosome | 20: 36751791-36773818 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Plasma proteins, Predicted intracellular proteins |
| Biological process | Cell cycle, Cell division, Chromosome partition, Mitosis |
Function
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.