MAGOHB — Mago homolog B, exon junction complex subunit
MAGOHB belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MAGOHB's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | Replication Licensing Cell cycle | ACYP1, DDB2, DSN1, GMNN, HIRIP3, ITGB3BP, LSM3, NUDT1 +8 more | View in SCUBA |
| Goblet cells | Proteostasis Housekeeping Housekeeping | ADRM1, EIF2S2, GNB2, NME1, NUDC, OAZ1, PARK7, PFDN2 +4 more | View in SCUBA |
| Macrophages | Mitotic Spindle Assembly Cell cycle | ACTL6A, AKR7A2, ANP32E, BOLA3, BUB3, CCDC167, CENPW, CENPX +34 more | View in SCUBA |
About the gene
| Synonyms | FLJ10292, MGN2 |
|---|---|
| Chromosome | 12: 10604193-10613609 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | RNA-binding |
| Biological process | mRNA processing, mRNA splicing, mRNA transport, Transport |
Function
Required for pre-mRNA splicing as component of the spliceosome. Plays a redundant role with MAGOH in the exon junction complex and in the nonsense-mediated decay (NMD) pathway.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.