DYNC2LI1 — Dynein cytoplasmic 2 light intermediate chain 1
DYNC2LI1 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DYNC2LI1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Inflammasome Activation Inflammation | ACBD3, ANKRD22, BFAR, CA8, CARD16, CASP1, CHRM3, CRELD2 +17 more | View in SCUBA |
About the gene
| Synonyms | CGI-60, D2LIC, DKFZP564A033, LIC3 |
|---|---|
| Chromosome | 2: 43774039-43810010 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Molecular function | Developmental protein, Motor protein |
| Biological process | Cilium biogenesis/degradation |
Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system, facilitating the assembly of these organelles. Involved in the regulation of ciliary length.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.