EN1 — Engrailed homeobox 1
EN1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EN1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | BMP Developmental Identity Developmental | ALCAM, BMP3, KANK4, LRRC38, LRRTM1, LY6H, PRSS2, SLC35F3 +3 more | View in SCUBA |
About the gene
| Chromosome | 2: 118842171-118847648 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Predicted intracellular proteins, Transcription factors |
| Molecular function | Developmental protein, DNA-binding |
Function
Required for proper formation of the apical ectodermal ridge and correct dorsal-ventral patterning in the limb
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.