LRRC38 — Leucine rich repeat containing 38
LRRC38 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LRRC38's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | BMP Developmental Identity Developmental | ALCAM, BMP3, EN1, KANK4, LRRTM1, LY6H, PRSS2, SLC35F3 +3 more | View in SCUBA |
| Hematopoietic progenitor cells | Lymphoid Progenitor Commitment Lymphcyte development | BASP1, CCR9, LSAMP, LZTFL1, MME, OSBPL3, SCN3A, SH3BP5 +3 more |
About the gene
| Chromosome | 1: 13474973-13514003 |
|---|---|
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Molecular function | Ion channel |
| Biological process | Ion transport, Transport |
Function
Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.