FAIM2 — Fas apoptotic inhibitory molecule 2
FAIM2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FAIM2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | CD34+ Quiescent Fibroblast ECM production | ABLIM1, C1QTNF3, CD34, CILP, CLDN11, CPVL, FOLH1, GPC3 +8 more | View in SCUBA |
About the gene
| Synonyms | KIAA0950, LFG, LFG2, LIFEGUARD, NMP35, TMBIM2 |
|---|---|
| Chromosome | 12: 49866896-49904217 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins, Transporters |
| Biological process | Apoptosis |
Function
Antiapoptotic protein which protects cells uniquely from Fas- induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.