CLDN11 — Claudin 11
CLDN11 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CLDN11's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | CD34+ Quiescent Fibroblast ECM production | ABLIM1, C1QTNF3, CD34, CILP, CPVL, FAIM2, FOLH1, GPC3 +8 more | View in SCUBA |
| Lymphatic endothelial | Lymphatic Valve Identity Valve formation | ALCAM, C12orf57, C17orf58, CFH, DEGS2, EBPL, EDNRB, GJA4 +13 more | View in SCUBA |
About the gene
| Synonyms | OSP, OTM |
|---|---|
| Chromosome | 3: 170418868-170454733 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted membrane proteins |
Function
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.