SCUBA

ABLIM1 — Actin binding LIM protein 1

ABLIM1 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

ABLIM1's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsGIMAP survival
Immune regulation
AKT3, ANKRD13D, ARL4C, C16orf54, CA5B, COPA, CRBN, DYNLT1 +16 moreView in SCUBA
EndothelialIL-13/STAT6 Signaling
Inflammation
ARL2BP, ASRGL1, ATP8B1, BMP1, BMPR2, CLIP1, CMIP, EHBP1L1 +18 moreView in SCUBA
EnterocytesYAP cytoskeletal remodeling
Migration & adhesion
AHCYL2, ARHGAP26, CCSER1, CDC42BPA, FGD4, ITGB8, PDE4D, PIP5K1B +5 moreView in SCUBA
FibroblastsCD34+ Quiescent Fibroblast
ECM production
C1QTNF3, CD34, CILP, CLDN11, CPVL, FAIM2, FOLH1, GPC3 +8 moreView in SCUBA
Glial cellsNeural Migration Scaffold
Cytoskeletal
ALCAM, ANK3, CAB39L, GAS2L3, GFRA3, IQGAP2, NRXN1, RELN +1 moreView in SCUBA

About the gene

SynonymsABLIM, LIMAB1, limatin
Chromosome10: 114431112-114768061
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Molecular functionActin-binding

Function

May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.