GAREM1 — GRB2 associated regulator of MAPK1 subtype 1
GAREM1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GAREM1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Sterol Transfer Lipid metabolism | CAPN13, GRAMD1B, MTARC2, NBAS, OSBPL9, PRLR | View in SCUBA |
About the gene
| Synonyms | C18orf11, FAM59A, FLJ21610, GAREM |
|---|---|
| Chromosome | 18: 32124877-32470882 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Mitogen |
Function
Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.