Sterol Transfer
Gene co-expression module in Enterocytes
| Category | Lipid metabolism |
|---|---|
| Genes | 7 |
| Annotation certainty | 2 of 5 |
| Annotation consistency | 3 of 7 genes have a known function matching the annotation |
Why this annotation
This is a small core module. GRAMD1B and OSBPL9 are non-vesicular sterol/lipid transfer proteins, and MTARC2 is an enterocyte mitochondrial reductase linked to lipid metabolism. The remaining genes (NBAS, GAREM1, CAPN13, PRLR) are heterogeneous long genes, so a partial long-gene/nuclear transcript contribution is possible. Lipid-transfer interpretation is tentative.
Genes
CAPN13, GAREM1, GRAMD1B, MTARC2, NBAS, OSBPL9, PRLR
Most correlated modules
- Colonocyte Solute Transport · correlation 0.90
- Mature colonocyte brush-border · correlation 0.87
- PGC1A/ERRG metabolic program · correlation 0.86
- Colonocyte differentiation signaling · correlation 0.84
- Brush-border nutrient uptake · correlation 0.83
- PPARA/FXR fatty acid oxidation · correlation 0.82
- Long-gene Nuclear Transcripts · correlation 0.81
- Brush-border Nutrient Uptake · correlation 0.79
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.