GGPS1 — Geranylgeranyl diphosphate synthase 1
GGPS1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GGPS1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Coinhibitory Checkpoint Exhaustion | BTN3A2, CDC25B, CDC42EP3, DDTL, FAM117A, FLOT2, GBP5, GRAP2 +12 more |
About the gene
| Synonyms | GGPPS1 |
|---|---|
| Chromosome | 1: 235327350-235344532 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Transferase |
| Biological process | Isoprene biosynthesis, Lipid metabolism |
Function
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.