BTN3A2 — Butyrophilin subfamily 3 member A2
BTN3A2 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BTN3A2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | B cell activation signaling B cell maturation | ANKRD44, BLK, EVI2B, GAPT, GPSM3, LBH, LTB, LY86 +9 more | View in SCUBA |
| CD4⁺ T cells | Interferon response Anti-viral | ACBD5, AQP3, BTN2A1, BTN3A3, CISH, EIF2AK2, ERAP2, GBP1 +23 more | View in SCUBA |
| Endothelial | MHC Class I Presentation Inflammation | B2M, BST2, BTN3A1, CYSTM1, HLA-A, HLA-B, HLA-C, HLA-F +1 more | View in SCUBA |
| Gamma-delta T cells | Coinhibitory Checkpoint Exhaustion | CDC25B, CDC42EP3, DDTL, FAM117A, FLOT2, GBP5, GGPS1, GRAP2 +12 more | |
| Glial cells | MHC-I Antigen Presentation Inflammation | B2M, C1R, C1S, CST3, HLA-A, HLA-B, HLA-C, IFI27 +4 more | View in SCUBA |
| Mucosal-associated invariant T cell | Lymphocyte Trafficking migration & adhesion | AASDHPPT, ANXA2, ARL14EP, ATP2A3, BIN1, DGKZ, OSTC, PTP4A2 +8 more |
About the gene
| Synonyms | BTN3.2 |
|---|---|
| Chromosome | 6: 26365159-26378320 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Adaptive immunity, Immunity |
Function
Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.