GTPBP4 — GTP binding protein 4
GTPBP4 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GTPBP4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Ribosome Biogenesis RNA processing & translation | ABCE1, BRIX1, BUD23, C12orf57, CDK4, DCAF13, DDX21, DKC1 +30 more | View in SCUBA |
About the gene
| Synonyms | CRFG, FLJ10686, FLJ10690, NGB, NOG1 |
|---|---|
| Chromosome | 10: 988434-1019932 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Biological process | Ribosome biogenesis |
Function
Involved in the biogenesis of the 60S ribosomal subunit. Acts as a TP53 repressor, preventing TP53 stabilization and cell cycle arrest
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.