IFRD2 — Interferon related developmental regulator 2
IFRD2 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
IFRD2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Ribosome Biogenesis RNA processing & translation | ABCE1, BRIX1, BUD23, C12orf57, CDK4, DCAF13, DDX21, DKC1 +30 more | View in SCUBA |
About the gene
| Synonyms | IFNRP, SKMc15, SM15 |
|---|---|
| Chromosome | 3: 50287732-50292918 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Translation regulation |
Function
Ribosome-binding protein that acts as an inhibitor of mRNA translation by promoting ribosome inactivation. Associates with the P- and E-sites of the ribosome and inserts a C- terminal helix into the mRNA exit channel to preclude translation (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.