KCP — Kielin cysteine rich BMP regulator
KCP belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KCP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Wound Regenerative Response Epithelial development | ADAMTS9, ARID5A, BNIP3, C2CD4B, CATSPERB, CDH3, CLDN1, DSG3 +36 more | View in SCUBA |
About the gene
| Synonyms | CRIM2, FLJ33365, NET67 |
|---|---|
| Chromosome | 7: 128862042-128910719 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Predicted secreted proteins |
Function
Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.