SCUBA

C2CD4B — C2 calcium dependent domain containing 4B

C2CD4B belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

C2CD4B's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsImmune Regulation
Immune regulation
ADAT2, AFTPH, CDKL2, CPEB4, DDHD1, FAM53B, FAS, FNDC3B +10 moreView in SCUBA
EndothelialNF-κB Activation
Inflammation
HSPA6, ICAM5, IER3, MAP3K8, NFKBIA, NFKBID, PMAIP1, PTGS2 +5 moreView in SCUBA
Lymphatic endothelialNF-κB Negative Feedback
Inflammation
BMP2, ICAM1, IRF8, KLF6, MAFF, NFIL3, NFKBIA, PRNP +4 moreView in SCUBA
PericytesEMT-like Remodeling
ECM remodeling
APOLD1, B3GNT5, CFAP20, FAM43A, INSIG1, LDLR, RALGDS, RND1 +2 moreView in SCUBA

About the gene

SynonymsFAM148B, NLF2
Chromosome15: 62163535-62165285
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins

Function

May be involved in inflammatory process. May regulate cell architecture and adhesion

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.