LRRC17 — Leucine rich repeat containing 17
LRRC17 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LRRC17's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | TGF-beta Fibroblast Niche ECM production | APCDD1, BAG2, C12orf75, CD55, CES1, CGREF1, COL11A1, CRYAB +8 more | View in SCUBA |
About the gene
| Synonyms | H_RG318M05.3, P37NB |
|---|---|
| Chromosome | 7: 102913000-102945111 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Predicted secreted proteins |
| Biological process | Osteogenesis |
Function
Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.