SCUBA

MBIP — MAP3K12 binding inhibitory protein 1

MBIP belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

MBIP's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsMembrane trafficking
Housekeeping
BCL2, CLSTN1, GLB1, GTF2I, HPSE, HSDL2, LENG8, MCF2L2 +19 moreView in SCUBA

About the gene

Chromosome14: 36298564-36320637
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins

Function

Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.