SCUBA

MESP1 — Mesoderm posterior bHLH transcription factor 1

MESP1 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

MESP1's module in each cell type

Cell typeModuleShares the module with
ColonocytesMature Colonocyte Metabolism
Nutrient processing
ACADS, ACSF2, ADIRF, AGFG2, B4GALNT2, CA1, CA2, CHP2 +37 moreView in SCUBA

About the gene

SynonymsbHLHc5, MGC10676
Chromosome15: 89749875-89751249
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins, Transcription factors
Molecular functionDevelopmental protein, DNA-binding
Biological processNotch signaling pathway, Transcription, Transcription regulation

Function

Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways (By similarity)

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.