SCUBA

ACSF2 — Acyl-CoA synthetase family member 2

ACSF2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

ACSF2's module in each cell type

Cell typeModuleShares the module with
EnterocytesMature enterocyte differentiation
Absorption
ABCC2, AOC1, CDC14A, CEP350, EEPD1, EPS8L2, GRAMD1C, MXI1 +5 moreView in SCUBA

About the gene

SynonymsACSMW, FLJ20920
Chromosome17: 50426158-50474845
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classEnzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins
Molecular functionLigase
Biological processFatty acid metabolism, Lipid metabolism

Function

Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.