MGAT2 — Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
MGAT2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MGAT2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | ER Morphology Stress Stress | ARMC1, ARPP19, ATL3, CMPK1, CYB5B, EIF2AK1, ELAVL1, ERGIC2 +8 more | View in SCUBA |
About the gene
| Synonyms | GNT-II |
|---|---|
| Chromosome | 14: 49620799-49623481 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Glycosyltransferase, Transferase |
Function
Plays an essential role in protein N-glycosylation. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) onto the free terminal mannose moiety in the core structure of the nascent N-linked glycan chain, giving rise to the second branch in complex glycans.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.