MPP7 — MAGUK p55 scaffold protein 7
MPP7 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MPP7's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | TCR signaling TCR/AP1/NFKb pathway | ACVR1C, ADA2, ANK3, CAMK4, CHD7, GCLM, GNAO1, NME4 +15 more | View in SCUBA |
| Lymphatic endothelial | Lymphatic Valve Development Valve formation | GPM6A, LRP5, MEF2C, NFIA, NFIB, PGM5, PRKAR1B, PXN +5 more | View in SCUBA |
| Monocytes | Classical Monocyte Trafficking Migration & adhesion | ANXA6, CKAP4, EMB, F5, GCA, MAP2K6, MSRB1, PADI4 +4 more | View in SCUBA |
| Neutrophils | Neutrophil Differentiation Developmental | DACH1, DGKD, FAR1, MSRA, PAM, PLCL2, PTBP2, RELL1 +1 more |
About the gene
| Synonyms | FLJ32798 |
|---|---|
| Chromosome | 10: 28050993-28334486 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.