NLN — Neurolysin
NLN belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NLN's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Monocytes | DNA Damage Response Stress | AGPAT5, ATM, CALM2, DCAF7, FAM13A, GPR155, MEF2C, NSL1 +4 more | View in SCUBA |
About the gene
| Synonyms | AGTBP, KIAA1226 |
|---|---|
| Chromosome | 5: 65722205-65871725 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Hydrolase, Metalloprotease, Protease |
Function
Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity). Acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1 (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.