NOB1 — NIN1 (RPN12) binding protein 1 homolog
NOB1 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NOB1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Ribosome Biogenesis RNA processing & translation | ABCE1, BRIX1, BUD23, C12orf57, CDK4, DCAF13, DDX21, DKC1 +30 more | View in SCUBA |
About the gene
| Synonyms | ART-4, MST158, NOB1P, PSMD8BP1 |
|---|---|
| Chromosome | 16: 69741871-69754926 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Molecular function | Endonuclease, Hydrolase, Nuclease |
Function
May play a role in mRNA degradation (Probable). Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.