POLR2C — RNA polymerase II subunit C
POLR2C belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
POLR2C's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | Basal Housekeeping RNA processing & translation | DUT, LSM10, NSL1, PSENEN, SDHAF2, SMIM19 | View in SCUBA |
About the gene
| Synonyms | RPB3 |
|---|---|
| Chromosome | 16: 57462660-57472009 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins |
| Biological process | Transcription |
Function
Core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.