PPP6R2 — Protein phosphatase 6 regulatory subunit 2
PPP6R2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PPP6R2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | ER Protein Biogenesis Protein processing & ER | AUP1, BAZ1B, DNAJC1, EMC10, EML3, FAM32A, FRG1, GLUD1 +10 more |
About the gene
| Synonyms | dJ579N16.1, KIAA0685, SAP190, SAPS2 |
|---|---|
| Chromosome | 22: 50343304-50445090 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
Function
Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.