SCUBA

PRPS1 — Phosphoribosyl pyrophosphate synthetase 1

PRPS1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

PRPS1's module in each cell type

Cell typeModuleShares the module with
Gamma-delta T cellsMetabolic-Translational Coupling
RNA processing & translation
APOL6, ARCN1, ARGLU1, DCAF12, DDX23, EIF2S1, EIF4G1, FHOD1 +20 more

About the gene

SynonymsCMTX5, DFN2, DFNX1, PPRibP, PRS-I
ChromosomeX: 107628428-107651993
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classDisease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Molecular functionKinase, Transferase
Biological processNucleotide biosynthesis

Function

Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.