PXK — PX domain containing serine/threonine kinase like
PXK belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PXK's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Actin cytoskeleton remodeling Cytoskeletal | ACTR2, BASP1, CAPZA1, CDV3, EIF3A, FAM107B, GRB2, HCLS1 +9 more | View in SCUBA |
About the gene
| Synonyms | FLJ20335, Slob |
|---|---|
| Chromosome | 3: 58332880-58426127 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins |
| Molecular function | Actin-binding |
Function
Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.