REG4 — Regenerating family member 4
REG4 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
REG4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Inflammatory Colonocyte State Inflammation | ABCA5, ALDOB, CYBRD1, DNAH7, FMO5, GALNT12, MUC2, NHSL1 +6 more | View in SCUBA |
About the gene
| Synonyms | GISP, REG-IV, RELP |
|---|---|
| Chromosome | 1: 119794017-119811580 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Predicted secreted proteins |
Function
Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.