RHOJ — Ras homolog family member J
RHOJ belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RHOJ's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endothelial Cell Migration migration & adhesion | CISD1, CTHRC1, GALNT1, MARCKS, MARCKSL1, NARF, PHLDB2, SHC1 +5 more | View in SCUBA |
About the gene
| Synonyms | ARHJ, FLJ14445, RASL7B, TCL |
|---|---|
| Chromosome | 14: 63204114-63293508 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Angiogenesis |
Function
Plasma membrane-associated small GTPase specifically involved in angiogenesis. Required for endothelial cell migration during vascular development via its interaction with GLUL. Elicits the formation of F-actin-rich structures, thereby regulating endothelial cell migration.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.