PHLDB2 — Pleckstrin homology like domain family B member 2
PHLDB2 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PHLDB2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endothelial Cell Migration migration & adhesion | CISD1, CTHRC1, GALNT1, MARCKS, MARCKSL1, NARF, RHOJ, SHC1 +5 more | View in SCUBA |
| Fibroblasts | Caveolae Mechanosensing Migration & adhesion | CAVIN1, FNBP1, KLHL5, LDLRAD3, MAP3K20, PDLIM3, PLEKHO1, PLP2 +6 more | View in SCUBA |
| Hematopoietic progenitor cells | HSC Quiescence Program Stemness | ADGRG6, AVP, CCDC175, CD164, CDH7, CHRM3, EGLN3, HEMGN +7 more | |
| Lymphatic endothelial | DNA Damage Apoptosis DNA/chromatin regulation | AZIN1, BAZ1A, HNRNPC, IVNS1ABP, MAPK6, OTUD4, SPEN, STX3 +4 more | View in SCUBA |
About the gene
| Synonyms | FLJ21791, LL5b, LL5beta |
|---|---|
| Chromosome | 3: 111732497-111976517 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
Seems to be involved in the assembly of the postsynaptic apparatus. May play a role in acetyl-choline receptor (AChR) aggregation in the postsynaptic membrane (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.