SCUBA

SAMM50 — SAMM50 sorting and assembly machinery component

SAMM50 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

SAMM50's module in each cell type

Cell typeModuleShares the module with
ColonocytesOxidative Phosphorylation
Mitochondrial & OxPhos
ABHD14B, ATP5F1D, CHCHD10, CYC1, ECI1, GFM1, GOT2, IDH3B +12 moreView in SCUBA

About the gene

SynonymsCGI-51, OMP85, SAM50, TOB55, TRG-3, YNL026W
Chromosome22: 43955442-44010531
Predicted locationIntracellular
Essential geneYes
Protein classEssential proteins, Predicted intracellular proteins, Transporters

Function

Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.