CHCHD10 — Coiled-coil-helix-coiled-coil-helix domain containing 10
CHCHD10 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CHCHD10's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Respiratory Chain Subunits Mitochondrial & OxPhos | ATP5F1D, ATP5ME, COX5A, NDUFB10, NDUFB7, PRDX2 | View in SCUBA |
| Fibroblasts | Quiescent Anti-inflammatory Fibroblast Developmental | ADIRF, DACH1, FXYD6, IGFBP3, KHDRBS3, LSP1, NDRG2, PDE1A +3 more | View in SCUBA |
| Goblet cells | Mitochondrial Biogenesis Mitochondrial & OxPhos | ARL6IP4, ATP5F1D, CISD3, CYBA, GADD45GIP1, METTL26, MIF, MRPL12 +3 more | View in SCUBA |
| Macrophages | Inflammasome Oxidative Stress Inflammatory | ABI3, ADISSP, AKR1A1, ARHGDIB, ARPC1B, ASCL2, BLVRA, C1orf54 +33 more | View in SCUBA |
| Monocytes | Non-classical Monocyte Lysosomal & pahgocytosis | ABI3, CAMK1, CD300A, DAPK1, FCGR3A, GNGT2, ICAM2, ITM2B +5 more | View in SCUBA |
| Natural Killer cells | Resident NK program Gut residency | ACP5, CDH17, CKLF, ID3, KRT81, KRT86, NEDD9, RGL4 +2 more | View in SCUBA |
| Pericytes | Pericyte Vascular Tone Developmental | ADAP2, CSPG4, FOXS1, LINGO1, MCAM, MFGE8, PGF, PTGIR +3 more | View in SCUBA |
About the gene
| Synonyms | C22orf16, MIX17A, N27C7-4 |
|---|---|
| Chromosome | 22: 23765834-23767972 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
Function
May be involved in the maintenance of mitochondrial organization and mitochondrial cristae structure
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.