SGSM1 — Small G protein signaling modulator 1
SGSM1 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SGSM1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Colonocyte HOX Identity Epithelial development | B3GNT7, CAPN13, CD14, CDHR1, CKB, CLDN8, CRACR2A, GPR161 +15 more | View in SCUBA |
About the gene
| Synonyms | KIAA1941, RUTBC2 |
|---|---|
| Chromosome | 22: 24806169-24927578 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | GTPase activation |
Function
Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as a GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.