SH2B3 — SH2B adaptor protein 3
SH2B3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SH2B3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Myeloid Receptor Signaling Innate immunity | ADGRE5, ANKFY1, ANKIB1, ATP1B1, CPT1A, DNAJC13, DOCK7, EPS15 +29 more | View in SCUBA |
About the gene
| Synonyms | IDDM20, LNK |
|---|---|
| Chromosome | 12: 111405923-111451623 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins |
Function
Links T-cell receptor activation signal to phospholipase C- gamma-1, GRB2 and phosphatidylinositol 3-kinase
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.