SHC4 — SHC adaptor protein 4
SHC4 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SHC4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Glial cells | Reactive Glial Activation Activation | ANP32B, ANTXR1, CTSD, FAM20C, GNG11, MAP1B, PKM, PTEN +2 more | View in SCUBA |
About the gene
| Synonyms | RaLP, SHCD |
|---|---|
| Chromosome | 15: 48823741-48963919 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, RAS pathway related proteins |
Function
Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.