SLC33A1 — Solute carrier family 33 member 1
SLC33A1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC33A1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Splicing Factor Regulation Housekeeping | ARAP1, CCNL1, CELF1, CLK1, FAM53C, IFRD1, INPPL1, KIDINS220 +12 more | View in SCUBA |
About the gene
| Synonyms | ACATN, AT-1, AT1, SPG42 |
|---|---|
| Chromosome | 3: 155821024-155854456 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters |
| Biological process | Transport |
Function
Acetyl-CoA transporter that mediates active acetyl-CoA import through the endoplasmic reticulum (ER) membrane into the ER lumen where specific ER-based acetyl-CoA:lysine acetyltransferases are responsible for the acetylation of ER-based protein substrates, such as BACE1. Necessary for O-acetylation of gangliosides.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.